Transient epileptic amnesia is considered rare though it is frequently underdiagnosed or misdiagnosed as transient global or psychogenic amnesia. In most cases of transient epileptic amnesia, no clear cause for the epilepsy is identified though MRI may show hippocampal atrophy or focal structural lesions in the temporal lobes. Interictal EEG, particularly when recorded in sleep, shows temporal lobe spikes whereas EEG during attacks of amnesia demonstrates either ictal discharges or postictal features. In addition, brief seizures typical of mesial temporal lobe epilepsy are detected in two thirds of patients. The duration of episodes of amnesia is usually less than an hour with usual recurrence of around 20 times each year in untreated patients. A study of 153 cases.Transient epileptic amnesia has been considered a syndrome of mesial temporal lobe epilepsy characterized by (1) recurrent episodes of isolated memory impairment of epileptic cause (ictal or postictal) while other cognitive functions remain intact (2) interictal memory disturbances of accelerated long-term forgetting and autobiographical and topographical amnesia and (3) late age of onset with a mean of 57 years. Syndromes of transient amnesia: towards a classification. Long-Term Outcome in Patients With Transient Global Amnesia: A Population-Based Study.Mayo Clin Proc. Risk factors of transient global amnesia - Three case reports. Transient global amnesia: current perspectives.Neuropsychiatr Dis Treat.
No alteration in consciousness must be present a population-based study concluded that an episode of TGA does not increase the risk of subsequent cerebrovascular events, seizures, or cognitive impairment (4)Īcute onset of anterograde amnesia must be present.There is no excess of cerebrovascular disease in patients with TGA There is a correlation between TGA and migraine. diagnosis may be made safely in the presence of a characteristic collateral history.remote precipitating events, with onset reported weeks prior to TGA, are considered anxiety triggered by conflict at home or work, health problems, and financial stressors (3).close precipitating events for TGA are considered emotional stress (i.e., triggered by gastric endoscopy, birth/death announcement, and difficult/exhausting workday), physical effort (i.e., gardening, house work, and sawing wood), physical exertion (including sexual activity), and water contact/temperature change (i.e., hot bath/shower and cold swim) (3).possible that it may result from different mechanisms such as venous congestion with valsalva-like activities before symptom onset, arterial thromboembolic ischaemia and vasoconstriction due to hyperventilation (1).Precipitating factors include sexual intercourse and heavy physical exercise, particularly swimming in cold water. study evidence showed a recurrence rate of 6.3% in a 10 year period.studies show a slight female predominance.Across studies, the mean age of an episode ranges from 61 to 67.3 years most commonly presents in the seventh decade of life.attacks usually last for 1-8 h but should be less than 24 h (1)Įpidemiological data put the annual incidence of TGA between 3.4 and 10.4/100,000 (2).patient remain alert, attentive, and cognition is not impaired.does not have any focal neurological symptoms.presents classically with an abrupt onset of severe anterograde amnesia.is unable to recall the episode once they have recovered.Is neurologically intact except for absent memory Patients with this condition are often described - wrongly - as being confused.
The patient is usually over 50 years old and an attack may last several hours. Transient global amnesia (TGA) is a temporary and isolated disorder of memory. Last edited 08/2020 and last reviewed 08/2020
0 kommentar(er)
